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Uptown 66

Mexican$Outdoor seatingNeighborhood1 deal

A Mexican cantina and taqueria on Biscayne with hand-pressed tortillas made from heirloom Oaxacan corn. The barbacoa — short-rib, oxtail, and beef cheek braised overnight with Mexican chilis — anchors the menu alongside birria tacos and stuffed burritos with chipotle crema. Open until 4am on weekends.

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The Vibe

Neighborhood

A Mexican cantina and taqueria on Biscayne where the tortillas are hand-pressed from heirloom Oaxacan corn and the barbacoa — short rib, oxtail, and beef cheek slow-braised overnight with Mexican chilis — anchors a menu that runs strong without shortcuts. Open until 4am on weekends; the garden patio is the spot when it's not raining.

What to Order

  • Overnight barbacoa tacos — short rib, oxtail, and beef cheek braised with Mexican chilis; on heirloom Oaxacan corn tortillasUptown 66 website
  • Birria tacos — braised beef with rich consommé for dippingUptown 66 website
  • Pollo asado taco — grilled chicken with crema and pickled carrotsUptown 66 website
Setting
Patio garden
View
Garden
Formality
Casual
Local gem

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MiamiNav is a Miami dining and entertainment guide organized around vibe, experience, and value, not just cuisine. It tracks deals, happy hours, and events across 19 Miami neighborhoods.